Outline
The initiative of organizing the International Roundtables (IRTs) was taken by Drs. Jean-Louis Imbach and Leroy Townsend, to have a biannual platform to discuss nucleoside chemistry and its biological applications, and later expanded to include nucleotides and nucleic acids. The first meeting was organized in Montpellier in 1974 and subsequently, IRTs have taken place in the US, Europe, and Japan. Today over 400 attendees from academia and industry gather to discuss cutting-edge research in medicinal chemistry, biochemistry, physicochemistry, and molecular biology, as well as synthetic and therapeutic applications of nucleosides and oligonucleotides. As there are not parallel sessions, everyone can attend every talk, if desired. Poster presentations form an important part of the scientific program and are displayed in place for several days.
Access・Schedule
September 3 - 6 2024
Tokyo University of Science
International Committee
(IS3NA Board Members)
- Jean-Jacques Vasseur
- Muthiah (Mano) Manoharan
- Ramon Eritja
- Suzanne Peyrottes
- Kathie Seley-Radtke
- Piet Herdewijn
Local Committee
(JSNAC Members)
- Naoki Sugimoto (Chair)
- Takeshi Wada (Chair)
- Takehiko Wada (Secretary)
- Hiroyuki Asanuma
- Toshihiro Ihara
- Akimitsu Okamoto
- Hirohide Saito
- Hisae Tateishi-Karimata
- Fumi Nagatsugi
- Noriaki Minakawa
- Asako Yamayoshi
- Hidetaka Torigoe
- Shuntaro Takahashi
- Kunihiko Morihiro
- Kazuki Sato
Schedule table
Important Dates:
* Travel award submission:
Deadline: April 5, 2024 (Fri.)
* Paper Application:
Oral Presentation: Deadline: May 15, 2024 (Wed.)
Poster Presentation: Deadline: June 14, 2024 (Fri)
* Registration:
Early Registration Deadline: May 15, 2024 (Wed.)
* Registration Web page:
* SPONSORSHIP AND EXHIBITION OPPORTUNITIES PDF files (in English)
* SPONSORSHIP AND EXHIBITION OPPORTUNITIES PDF files (in Japanese)
Invited speaker
- Prof. Tigran Chalikian, University of Toronto, Canada
“Conformational Propensities of Double-stranded G- and C-rich DNA Domains” - Prof. Janez Plavec, Slovenian NMR Centre at the National Institute of Chemistry, Slovenia
“NMR illuminating the dynamics of DNA structural features” - Prof. Kyeong Kyu Kim, Sungkyunkwan University, Suwon, Korea
“Noncanonical nucleic acids: structure, function and modulation” - Prof. Xiaogang Qu, Changchun Institute of Applied Chemistry, Chines Academy of Science, Changchun, China
“Targeting Non-Canonical Nucleic Acids Structures and Their Applications” - Prof. Chaoyong Yang, Xiamen University, China
“Dendrimeric DNA Coordinate Barcoding Design for Spatial RNA Sequencing” - Prof. Daniela Montesarchio, University of Napoli Federico II, Italy
“Non-canonical DNA-based aptamers for therapeutic applications” - Prof. Sara N. Richter, University of Padova, Italy
“Non-canonical nucleic acid structures in viruses” - Prof. Katrin Paeschke, University Hospital Bonn, Germany
“Relevance and Consequences of non-canonical nucleic acid structures in human cells” - Prof. Yan Xu, University of Miyazaki, Japan
“In Cell 19F NMR for Non-Canonical Structures” - Prof. Kazuo Nagasawa, Tokyo University of Agriculture and Technology, Japan
“Control of functions of dynamically formed high-order nucleic acids by polyoxazole compounds” - Dr. Chandra Vargeese, Wave Life Sciences, USA
“Base, sugar, and backbone modifications of stereopure oligonucleotides to improve pharmacology across modalities” - Prof. Roger Stromberg, Karolinska Institutet, Sweden
“Artificial RNases based on modified oligonucleotides” - Prof. Serge Van Calenbergh , Ghent University, Belgium
“Tubercidin analogues outsmart protozoan pathogens responsible for important human and livestock diseases” - Prof. Marcal Pastor-Anglada, University of Barcelona, Spain
“Membrane transporters for natural nucleosides and nucleoside-derived drugs“ - Prof. Christian Ducho , Saarland University, Germany
“New adventures in oligonucleotide modifications” - Prof. Satoshi Ichikawa , Hokkaido University, Japan
“Nucleoside natural products as a lead for antibacterial drug” - Prof. Zlatko Janeba , IOCB Prague, Czech Republic
“Inhibitors of enzymes of the purine salvage pathway” - Prof. Jory Lietard , University of Vienna, Austria
“DNA, RNA and XNA microarrays: high-throughput oligonucleotide chemistry” - Prof. Kurt V. Gothelf, Aarhus University, Denmark
“Modification of oligonucleotides at phosphorus” - Prof. Meena, Stoke Therapeutics, USA
“Utilization of a Pharmacokinetic (PK) Model for STK-001 (ASO) in Patients with Dravet Syndrome (DS) To Support the Selection of Dosing Regimens in Clinic” - Prof. Damien Baigl, Ecole Normale Superieure , France
“DNA-encoded synthetic systems with life-like properties” - Dr. Mano Manoharan, Alnylam Pharmaceuticals, USA
“Biomimetic Chemistry of RNA Therapeutics”
About IS3NA
Established in 2000, the IS3NA was the brainchild of Prof. J.-L. Imbach and Prof. L. B. Townsend, the two "fathers" of the International Roundtable meetings. They wanted the IRTs to continue but wanted control of the IRTs to become the responsibility of a new Society formed for that purpose. This new Society would not only take over the operation of the IRTs but would also bring together people interested in each aspect of research related to nucleotides, oligonucleotides, and nucleic acids.
The aim of the IS3NA is to capitalize on the knowledge of practicing members across several disciplines to understand the impact of nucleic acids in a plethora of cutting-edge scientific questions ranging from the origins of life to the development of novel therapeutics.
AIMS OF IS3NA:
- To coordinate and sponsor meetings and to promote publications.
- To provide means for the dissemination of knowledge dealing with current research.
- To act as a mediator for communication, cooperation, and understanding between scientists of all nationalities.
- To encourage national and international collaborations on research and application among academic, industrial, governmental and private institutional organizations.